Clinical Characteristics and Microbial Profiles of Paediatric Patients with Methicillin-Resistant Staphylococcus aureus Pneumonia in China

Background: Staphylococcus aureus can cause fatal pneumonia. The evolution of bacteria and the overuse antibiotics have enhanced drug resistance methicillin-resistant (MRSA) methicillin-sensitive (MSSA). Objectives: This study aimed to recapitulate microbiological profile clinical characteristics paediatric patients with MRSA. Methods: retrospective was conducted investigate 1372 S. pneumonia from January 2017 December 2021. Sputum specimens were collected processed for performing bacterial culture sensitivity tests. Medical records reviewed laboratory examination results. Results: MRSA MSSA mainly occurred in infants; however, comparisons sex, age, sampling time between showed no significant differences (P > 0.05). results sputum revealed that all isolates susceptible vancomycin, tigecycline, linezolid, teicoplanin, ceftaroline. Methicillin-sensitive completely sensitive rifampicin oxacillin. Methicillin-resistant resistant penicillin oxacillin, while less penicillin. both maintained high rates gentamicin, sulfamethoxazole-trimethoprim, levofloxacin, moxifloxacin, exception clindamycin erythromycin. According our results, moreover, gentamicin sulfamethoxazole-trimethoprim significantly higher than < common symptoms fever, cough, wheezing. had counts white blood cells (WBCs), C-reactive protein (CRP), procalcitonin (PCT) Conclusions: antimicrobial test reflect guide use antibiotics. Infectious biomarkers severity infection prognosis.